DIABETIC PERIPHERAL NEUROPATHY

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Evidence of neurodegenerative disease has been found in the peripheral nervous system in diabetes – commonly called diabetic neuropathies that involve damage to peripheral sensory neurons. Currently more than 50% of diabetic patients develop some form of peripheral nerve disease, which can lead to loss of protective sensation and limb amputation.

No FDA-approved treatment exists for diabetic neuropathy, a condition that afflicts over half of the 29 million Americans (over 415 million worldwide) who suffer from diabetes. Although drugs exist to relieve the pain, the goal for those that aim to treat this major unmet clinical need is a therapy that can prevent the onset of nerve damage and re-grow damaged nerves.

 

 

There is no disease-modifying or curative treatment approved for diabetic neuropathy. Current approaches at best mitigate the pain or attempt to control the underlying diabetes.

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Source: International Diabetes Foundation