Nerve damage can make you lose feeling in your feet, so even minor cuts can turn into sores or ulcers without your realizing it. In severe cases, an infection can spread to the bone or lead to tissue death. Removal (amputation) of a toe, foot or even the lower leg may be necessary.

Diabetic Peripheral Neuropathy (DPN)

Evidence of neurodegenerative disease has been found in the peripheral nerves of diabetics. Currently more than 50% of diabetic patients develop some form of peripheral nerve disease, which can lead to loss of sensation, tingling, pain, limb amputation, and death. No FDA-approved treatment exists for diabetic neuropathy, a condition that afflicts over half of [...]

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