Peripheral neuropathy is a condition marked by the degeneration of peripheral sensory nerves that result from a complication of a certain disease or injury. Symptoms vary from patient to patient and include: tingling, numbness, hypersensitivity and intense, jarring pain in the extremities. For some, all sensation in the hands and feet are lost, often resulting in ulcers and amputation. The prevalence of peripheral neuropathy is 2% to 4% worldwide and 6% in the US alone.An estimated 30 million Americans suffer from a type of peripheral neuropathy. There are over 100 different types of neuropathies. WinSanTor is currently undergoing clinical trials for a lead drug aimed at treating diabetic peripheral neuropathy (DPN), chemo-induced peripheral neuropathy (CIPN) and HIV-PN (HIV-induced peripheral neuropathy). Our lead drug treats peripheral neuropathy, focusing on sensory polyneuropathy.
Peripheral neuropathy is a condition that involves damage to the peripheral nervous system. Our peripheral nerves carry signals to and from our central nervous system. Hence malfunctioning of these nerves causes disruption and affects how the body reacts to reflexes and other stimuli, like pain and temperature.
Diabetic peripheral neuropathy is a progressive disease that involves pain, loss of sensation and weakness. However, a proper clinical examination may identify early signs without the presence of any symptoms. About 60% to 70% of diabetic patients are known to suffer from peripheral neuropathy. If not treated in time or managed well, it can lead to lower limb amputations. Each year, nearly 54,000 diabetics undergo amputations, 75% of which are preventable.
Symptoms develop gradually and can go unnoticed until they cause serious damage. If you notice any slight change in your symptoms or condition, consult your physician.
Nerve damage in diabetic neuropathy is caused due to high glucose levels. Diabetics are often recommended to maintain their blood glucose levels within a healthy range to prevent any further health complications. Symptoms can vary person to person but here are a few common ones: